GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BRCA | cis | rs6684514 | 1 | rs10908494 | chr1:156263097 | BGLAP | chr1:156182784-156213112:+ | 0.21 | 5.56 | 3.35E-8 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BRCA | cis | rs6684514 | 1 | rs10908494 | chr1:156263097 | C1orf85 | chr1:156259882-156265449:- | -0.11 | -3.45 | 0.000576 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BRCA | cis | rs6684514 | 1 | rs10908495 | chr1:156263940 | BGLAP | chr1:156182784-156213112:+ | 0.2 | 5.47 | 5.65E-8 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BRCA | cis | rs6684514 | 1 | rs10908495 | chr1:156263940 | C1orf85 | chr1:156259882-156265449:- | -0.11 | -3.53 | 0.00044 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BRCA | cis | rs6684514 | 1 | rs10908496 | chr1:156264000 | BGLAP | chr1:156182784-156213112:+ | 0.2 | 5.3 | 1.44E-7 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BRCA | cis | rs6684514 | 1 | rs10908498 | chr1:156278175 | BGLAP | chr1:156182784-156213112:+ | 0.2 | 5.45 | 6.15E-8 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BRCA | cis | rs6684514 | 1 | rs10908499 | chr1:156279176 | BGLAP | chr1:156182784-156213112:+ | 0.2 | 5.45 | 6.15E-8 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BRCA | cis | rs6684514 | 1 | rs10908500 | chr1:156280671 | BGLAP | chr1:156182784-156213112:+ | 0.19 | 5.05 | 5.11E-7 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BRCA | cis | rs6684514 | 1 | rs10908500 | chr1:156280671 | C1orf85 | chr1:156259882-156265449:- | -0.11 | -3.45 | 0.000588 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BRCA | cis | rs6684514 | 1 | rs10908502 | chr1:156300082 | BGLAP | chr1:156182784-156213112:+ | 0.2 | 5.24 | 1.92E-7 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BRCA | cis | rs6684514 | 1 | rs10908502 | chr1:156300082 | CCT3 | chr1:156278752-156308195:- | -0.11 | -3.56 | 0.000391 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BRCA | cis | rs10910092 | 1 | rs10910092 | chr1:2501516 | LOC115110 | chr1:2481359-2488450:- | -0.09 | -3.94 | 8.55E-5 | Ulcerative colitis |
| BRCA | cis | rs10910092 | 1 | rs10910092 | chr1:2501516 | MMEL1 | chr1:2522081-2564481:- | -0.14 | -4.75 | 2.36E-6 | Ulcerative colitis |
| BRCA | cis | rs11799420 | 1 | rs10913489 | chr1:171653384 | VAMP4 | chr1:171669298-171711214:- | 0.12 | 3.4 | 0.00071 | Hippocampal atrophy |
| BRCA | cis | rs11799420 | 1 | rs10913490 | chr1:171653401 | VAMP4 | chr1:171669298-171711214:- | 0.12 | 3.4 | 0.00071 | Hippocampal atrophy |